---
title: "Is licorice (DGL) good for acid reflux?"
entity: "blog"
canonical_url: "https://www.drdanwool.com/blog/dgl"
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lastmod: "2024-11-12T19:00:00.000Z"
---

Medically reviewed by [Dr. Dan Wool, NMD](https://www.linkedin.com/in/drdanwool/)

 Arizona-licensed Naturopathic Physician and  Gastroenterology Specialist

 Updated: February 27, 2026

Summary: 

- Understanding Licorice and DGL:  Licorice (Glycyrrhiza glabra) is an ancient medicinal root known for its sweet taste and powerful healing properties. Its deglycyrrhizinated form (DGL) removes glycyrrhizin—the compound responsible for side effects—making it a safe and effective option for digestive support.
- DGL for Acid Reflux and Ulcers:  Unlike conventional acid-suppressive drugs such as PPIs and antacids, which reduce stomach acid and may impair nutrient absorption, DGL helps heal and protect the gut lining without disrupting digestion.
- Research-Backed Benefits of DGL for GERD:   Studies show that DGL improves symptoms of GERD and other gastric issues by enhancing mucus production, soothing inflammation, and protecting the esophagus—offering results comparable to standard medications with fewer risks.
- DGL Safety and Usage Considerations:  While DGL is generally considered safe, those with hypertension, heart disease, or on potassium-lowering medications should consult a naturopathic or medical professional before use.

## What is Acid Reflux?

[Acid reflux](/acid-reflux) (also known as gastroesophageal reflux (GER) is a digestive disorder and is frequently used mistakenly as a synonym for the terms ‘heartburn’ and ‘GERD’ even though they are not identical. Acid reflux occurs when stomach contents flow back into the esophagus. If this condition becomes more severe, it is diagnosed as gastroesophageal reflux disease (GERD).

Heartburn is the sensation associated with acid reflux. It’s often described as a mild burning feeling in the middle of the chest, and it happens shortly after a meal or when you lie down too soon after eating. When the sphincter muscle, at the lower end of the esophagus, relaxes at the wrong time, it allows stomach acid to go back up into the esophagus. This might manifest in heartburn and other unpleasant symptoms. If the reflux increases in frequency or constantly appears, this can lead to GERD. For peace of mind, consult your doctor if symptoms occur twice a week or more.

According to statistics, around 20% of adults [1] in the US suffer from acid reflux, which decreases their quality of life and overall well-being and results in an economic burden to the individual and the healthcare system.

## What is licorice (and DGL)?

Licorice (Glycyrrhiza glabra) a.k.a. “sweet root” is a plant that has been used for culinary and medicinal purposes for thousands of years. The root of the licorice plant contains a specific ingredient many times sweeter than sugar. Apart from its unique taste that has inspired generations of confectioners’ sweet creations and has become a favorite for young and old, especially in Northern Europe, licorice root has always been very popular in traditional Eastern and Western medicine. It is used as a dietary supplement to treat many conditions, from coughs, and colds, to bacterial and viral infections, menopausal symptoms, and liver disease.

Licorice root has dual action both as “demulcent’ i.e. a soothing, coating agent, and as an “expectorant”, helping expel phlegm from the body. Although not all uses of licorice are backed by scientific evidence, it is still used today for several conditions. Licorice comes mainly from Asia, Turkey, and Greece and is available in several forms, the most common ones being tablets or capsules. 

However, before you start thinking of using licorice to treat any illness, you should know that there is an active ingredient called ‘glycyrrhiza’ contained in licorice which can cause serious side effects if not checked by a professional such as naturopathic doctor or herbalist. There is a form of licorice known as “deglycyrrhizinated licorice” or DGL that doesn’t have these side effects and it's used in the treatment of digestive conditions such as peptic ulcers, canker sores, and acid reflux (GERD). Both forms are effective.

## Traditional Medical Treatment for Acid Reflux

Nowadays, we refer to pharmaceuticals as ‘traditional’ and supplements or natural ingredients as ‘complementary’ or ‘alternative’. It’s a strange twist since traditionally plants, minerals, and other natural ingredients were used for many millennia before manmade drugs and chemicals became the norm.

Without denying the benefits that medications can have when treating chronic or acute acid reflux, it’s also good to be aware that very often they address only the symptoms without having long-term effects on the underlying cause. 

For example, your physician or pharmacist may recommend antacids to address chronic acid reflux. Typical antacids contain a carbonate, or alkaline, to neutralize "excess" stomach acid. Antacids are widely used because they are cheap, convenient and effective for temporary relief. Most can be purchased over-the-counter without a prescription in tablet or liquid form (which works faster) and include some of the best known brand names in over-the-counter medicine including Tums, Gaviscon, Rolaids, Alka-Seltzer and Mylanta, among others.

However, the antacids only change your pH scale from acidic to alkaline, without addressing the damage caused by the condition. hey are good for acute heartburn, such as when one overeats, but many chronic acid reflux sufferers may find that they pop more and more tablets without effective relief. That's because we end up with a neutral lake in the stomach instead of acid to break down proteins and thus food can take longer to break down, and often not effectively.

Other frequently prescribed drugs are proton pump inhibitors (PPIs) and histamine (H2) blockers for turning down the digestive juices. 

The above medications suppress the role of stomach acid in your digestive system, inhibiting nutrient absorption. The insufficient breakdown of nutrients and proteins can lead to calcium deficiencies, and thus to illnesses such as osteoporosis and digestive tract infections since your stomach lacks the necessary acids to fight pathogenic bacteria.

## Acid Reflux and Licorice (DGL): What the Studies Say

Treating digestive tract conditions through naturopathic methods cannot only eliminate the unpleasant symptoms but most importantly address the root causes while looking at the patient holistically. Unlike many prescription and over-the-counter medications, that have many side effects and create a new problem while treating an existing one, naturopathy strives to always treat the ‘whole patient’ and not just an isolated ailment.

Below are a few references and a summary of some of the most relevant findings from official medical studies and sources:

- Acid-suppressive drugs (PPIs) vs herbal formulas (including DGL). Russel Streight’s observational study [2] suggests that deglycyrrhizinated licorice (DGL), when added to a herbal formula, can significantly improve symptoms of GERD. Over two years, 58 participants with chronic gastric issues reported better relief with the DGL-containing formula compared to common antacids. This is a strong indication that DGL may be a beneficial alternative for soothing and protecting the gastric mucosa without the need to lower gastric acid levels substantially. According to the study, DGL is a potentially safer option, with fewer adverse effects than traditional acid-suppressive drugs.
- DGL has a long history of therapeutic use.  History of Therapeutic Use of Licorice in Europe [3] shows documented evidence that licorice root has been used in Europe for many millennia. Since ancient times, many different ethnic groups (Scythian, Greek, Roman, and from the Middle Ages in Germany, Italy, Spain, and England) have used the plant as a remedy and the effects are far beyond a placebo. In the second part of the study, there is an outline of diseases traditionally treated with licorice which also includes gastrointestinal ailments such as acid reflux.
- Licorice - a bridge between traditional medicine and modern science. Known for its sweet flavor, licorice is widely used in the food industry as well as in traditional Chinese medicine (TCM) and complementary medicine. In bioactivity and potential health benefits of licorice [4], the authors refer to Its therapeutic applications that are well-documented in TCM, and the interest modern science shows in its broad range of applications.

## Licorice (DGL) vs. traditional treatment options

### Benefits of DGL

- Protects gut lining. DGL increases mucus production which can protect the stomach and esophagus from acid;
- Demulcent and energy balancer. It may treat ulcers, balance hormones during menstruation and menopause, ease sore throats, and treat respiratory tract infections and even viral hepatitis;
- On par with PPIs. Can be more effective in treating acid reflux than acid-suppressive drugs, such as proton pump inhibitors (PPIs) [2].

### Potential Risks of DGL

- Hypertension. If you have high blood pressure or heart disease you should be cautious and discuss it with your doctor before taking licorice extract; this is more common when the active ingredient glycerrhiza is removed, as it is in DGL. 
- Pregnancy and breastfeeding. Avoid using licorice or DGL if you’re pregnant or breastfeeding;
- Potassium and medication interactions. Licorice can interact with other medications and affect potassium levels, so always consult a naturopath and your physician before taking it. Avoid using licorice if you are on corticosteroids, diuretics, or other medicines that lower your potassium levels;
- Consult a professional. Since the FDA doesn’t regulate licorice and DGL, the quality and potential doses might vary. Always consult a naturopathic doctor or botanical expert such as Dr. Dan Wool before embarking on a glycerrhiza/DGL treatment plan.

## Frequently Asked Questions About DGL for Acid Reflux 

### 1. Does DGL help with GERD/acid reflux?

Yes. DGL (deglycyrrhizinated licorice) is licorice root with glycyrrhizin removed to prevent side effects. It acts as both demulcent (soothing, coating agent) and expectorant. DGL treats [GERD](/acid-reflux), peptic ulcers and canker sores by protecting stomach and esophagus lining. Safe for long-term use unlike regular licorice, which can cause blood pressure issues in sensitive individuals.

### 2. Can I take DGL licorice long-term for acid reflux?

Yes. Unlike PPIs or regular licorice, DGL is safe for extended use without side effects. It addresses root causes by healing digestive tract lining rather than just suppressing acid. However, work with naturopathic practitioners to combine DGL with dietary changes, stress management, and lifestyle modifications for comprehensive, lasting GERD relief. The goal of any tool, herbal or otherwise is to heal and not need them. 

### 3. Does licorice root interact with medications?

Regular licorice can interact dangerously with blood pressure medications, diuretics, corticosteroids and heart medications due to the substance glycyrrhizin. DGL is much safer but still inform your healthcare provider about all supplements. Avoid regular licorice if taking meds like digoxin, warfarin or insulin. Your naturopathic doctor should assess any medication interactions before recommending herbal protocols.

### 4. Is deglycyrrhizinated licorice (DGL) considered safe? Is taking DGL chewable or gummies safe? 

Yes. Unlike PPIs or regular licorice, which contains glycyrrhizin which can cause cardiovascular symptoms in sensitive individuals, DGL (the form without it) is safe for extended use without side effects.  Many of our patients take DGL tabs or gummies a 20-30 minutes before meals without issues. 

### 5. What are the potential side effects of deglycyrrhizinated licorice (DGL)?

DGL is generally well-tolerated since the compound linked to serious side effects has been removed. Mild side effects may include nausea, stomach upset or headache. Unlike regular licorice, DGL typically does not raise blood pressure or affect potassium levels. Always consult your doctor before use.

## The "Bottom Line" on DGL

Licorice can be a great alternative to pharmaceuticals when it comes to the treatment of acid reflux or other conditions since it not only treats the symptoms but most importantly, the underlying causes. As with any form of medication, traditional or naturopathic, it’s always best to discuss it with your physician and with a certified naturopath before taking it. This will help your carers determine the best treatment plan to avoid undesirable and potentially dangerous side effects.

Take the first step toward lasting relief from acid reflux. Call [Dr. Dan Wool](/about)’s office in Scottsdale or schedule your [free 15-minute consultation](/booking) online today.

Find out about other common natural and herbal remedies that support gut health:

- [Slippery elm](https://drdanwool.com/blog/slippery-elm)
- [L-Glutamine ](https://drdanwool.com/blog/lglutamine)
- [Marshmallow (Althea off.)](https://drdanwool.com/blog/marshmallow)
- [Aloe Vera](https://drdanwool.com/blog/is-aloe-vera-good-for-acid-reflux)
- [Licorice (DGL)](https://drdanwool.com/blog/is-licorice-dgl-good-for-acid-reflux)
- [Sodium bicarbonate (Baking Soda)](https://drdanwool.com/blog/bakingsodasodiumbicarbonate)
- [Apple Cider Vinegar](https://drdanwool.com/blog/applecidervinegar)
- [Zinc Carnosine](/blog/zinc-carnosine)

Read our [Acid Reflux/GERD mega FAQ](/blog/frequently-asked-questions-about-gerd-acid-reflux-heartburn)and get answers:

About the Author

## Dr. Dan Wool, NMD

Dr. Dan Wool is a naturopathic doctor who specializes in gastroenterology, hormones and men's health in Scottsdale, Arizona. [Set up a free 15-minute discovery call with Dr. Wool today! ](https://drdanwool.com/booking)

[Read more about Dr. Wool's Gut Health Journey](/about)

## Sources:

[[1](https://www.ncbi.nlm.nih.gov/books/NBK441938/, NBK441938PMID: 28722967)] Catiele Antunes; Abdul Aleem; Sean A. Curtis., Gastroesophageal Reflux Disease, July 3 2023, https://www.ncbi.nlm.nih.gov/books/NBK441938/, NBK441938PMID: 28722967

[[2](https://search.informit.org/doi/abs/10.3316/informit.950298610899394)] Russell Setright, Prevention of symptoms of gastric irritation (GERD) using two herbal formulas: An observational study, Journal: Journal of the Australian Traditional-Medicine Society, June 2017, ISSN (print):1326-3390, Volume:23 | Issue:2, Page Range:68-71, https://search.informit.org/doi/abs/10.3316/informit.950298610899394

[[3](https://pubmed.ncbi.nlm.nih.gov/15978760/)] Fiore C, Eisenhut M, Ragazzi E, Zanchin G, Armanini D. A history of the therapeutic use of licorice in Europe. J Ethnopharmacol. 2005;99(3):317-24.  https://pubmed.ncbi.nlm.nih.gov/15978760/

[[4](https://pubmed.ncbi.nlm.nih.gov/24377378/)] Kao TC, Wu CH, Yen GC. Bioactivity and potential health benefits of licorice. J Agric Food Chem. 2014;62(3):542-53., https://pubmed.ncbi.nlm.nih.gov/24377378/